Publications by Year (2025)

Publications | 2025

2026 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020

2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 |2012 | Pre-2011

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123 - The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin

123. Carlson, Erik S.; Haslecker, Raphael; Lecchi, Chiara; Aguilar Ramos, Miguel A.; Vennelakanti, Vyshnavi; Honaker, Linda; Stornetta, Alessia; Millán, Estela S.; Johnson, Bruce A.; Kulik, Heather J.; Balbo, Silvia; Villalta, Peter W.; D’Souza, Victoria M.; Balskus, Emily P. The Specificity and Structure of DNA Cross-Linking by the Gut Bacterial Genotoxin Colibactin. Science 2025, 390, eady3571. DOI: https://doi.org/10.1126/science.ady3571.

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122 - The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links

122. Altshuller, Maria; He, Xu; MacKrell, Elliot J.; Wernke, Kevin M.; Airan, Yougant; Wong, Joel W. H.; Sellés-Baiget, Selene; Wang, Ting-Yu; Chou, Tsui-Fen; Duxin, Julien P.; Balskus, Emily P.; Herzon, Seth B.; Semlow, Daniel R. The Fanconi Anemia Pathway Repairs Colibactin-Induced DNA Interstrand Cross-Links. Nat. Commun. 2025, 16, 10563. DOI: https://doi.org/10.1038/s41467-025-65606-1.

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121 - Systematic identification and characterization of regulators of aryl hydrocarbon receptor signaling

121. Verma, Manasvi; Desai, Kushaal; Ding, Yufang; Wang, Xingren; Bae, Minwoo; Rakoff-Nahoum, Seth; Balskus, Emily P.; Fischbach, Michael A.; Jost, Marco. Systematic Identification and Characterization of Regulators of Aryl Hydrocarbon Receptor Signaling. bioRxiv 2025, 2025.09.15.676391. DOI: https://doi.org/10.1101/2025.09.15.676391.

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120 - Characterizing and engineering post-translational modifications with high-throughput cell-free expression

120. Wong, Derek A.; Shaver, Zachary M.; Cabezas, Maria D.; Daniel-Ivad, Martin; Warfel, Katherine F.; Prasanna, Deepali V.; Sobol, Sarah E.; Fernandez, Regina; Tobias, Fernando; Filip, Szymon K.; Hulbert, Sophia W.; Faull, Peter; Nicol, Robert; DeLisa, Matthew P.; Balskus, Emily P.; Karim, Ashty S.; Jewett, Michael C. Characterizing and Engineering Post-Translational Modifications with High-Throughput Cell-Free Expression. Nat. Commun. 2025, 16, 7215. DOI: https://doi.org/10.1038/s41467-025-60526-6.
Preprint: bioRxiv 2024. DOI: https://doi.org/10.1101/2024.03.25.586624.

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119 - Bacterial peptide deformylase inhibitors induce prophages in competitors

119. Chen, Julie; Pfeifer, Katarina; Steensen, Kerrin; Crooke, Anne Marie; Wolfram, Michael; Bobonis, Jacob; Lopatina, Anna; Bartlau, Nina; Hussain, Fatima A.; Balskus, Emily P.; Polz, Martin F.; Blainey, Paul C. Bacterial Peptide Deformylase Inhibitors Induce Prophages in Competitors. bioRxiv 2025, 2025.06.06.656871. DOI: https://doi.org/10.1101/2025.06.06.656871.

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118 - A new heme enzyme family forms hydrazine groups in diverse biosynthetic pathways

118. Kenney, Grace E.; Wang, Kwo-Kwang A.; Ng, Tai L.; van der Donk, Wilfred A.; Balskus, Emily P. A New Heme Enzyme Family Forms Hydrazine Groups in Diverse Biosynthetic Pathways. bioRxiv 2025, 2025.05.27.656397. DOI: https://doi.org/10.1101/2025.05.27.656397.

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117 - Biochemical Studies of a Cyanobacterial Halogenase Support the Involvement of a Dimetal Cofactor

117. Wang, Michelle L.; Glasser, Nathaniel R.; Nair, Mrutyunjay A.; Krebs, Carsten; Bollinger, J. Martin, Jr.; Balskus, Emily P. Biochemical Studies of a Cyanobacterial Halogenase Support the Involvement of a Dimetal Cofactor. Biochemistry 2025, 64, 2173–2180. DOI: https://doi.org/10.1021/acs.biochem.4c00720.

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116 - Enantiocomplementary Gut Bacterial Enzymes Metabolize Dietary Polyphenols

116. Dong, Xueyang; Bae, Minwoo; Le, Chi; Aguilar Ramos, Miguel A.; Balskus, Emily P. Enantiocomplementary Gut Bacterial Enzymes Metabolize Dietary Polyphenols. J. Am. Chem. Soc. 2025, 147, 7231–7244. DOI: https://doi.org/10.1021/jacs.4c09892.

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115 - Distinct Classes of Gut Bacterial Molybdenum-Dependent Enzymes Produce Urolithins

115. Bae, Minwoo; Dong, Xueyang; Avila-Pacheco, Julian; Inyama, Fechi; Hill-Maini, Vayu; Clish, Clary; Balskus, Emily P. Distinct Classes of Gut Bacterial Molybdenum-Dependent Enzymes Produce Urolithins. bioRxiv 2025, 2025.01.17.632430. DOI: https://doi.org/10.1101/2025.01.17.632430.

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114 - A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury

114. Richards-Corke, Khyle C.; Jiang, Yindi; Yeliseyev, Vladimir; Zhang, Yancong; Franzosa, Eric A.; Wang, Zhipeng A.; Yapa Abeywardana, Maheeshi; Cole, Phillip A.; Huttenhower, Curtis; Bry, Lynn; Balskus, Emily P. A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury. ACS Chem. Biol. 2025, 20, 48–55. DOI: https://doi.org/10.1021/acschembio.3c00556.

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